effect overlay
activetrials
Multiple sclerosis
Multiple Sclerosis
Zenith CAR-T

A Phase 1b, Open-label, Multi-center, Randomized Study Evaluating the Safety and Tolerability of AZD0120, an Autologous CD19/BCMA Targeting Chimeric Antigen Receptor T-cells, in Adults with Refractory Relapsing or Progressing Multiple Sclerosis

HREC: 2025.309
Principal Investigator: Dr Izanne Roos
Coordinator contact: Katherine Fazzolari
Funding: Commercial
Multiple sclerosis
Multiple Sclerosis
BALANCE

A Phase 2, Randomized, Double-blind, Four-Arm, Placebo-Controlled, Multicenter Study Assessing the Efficacy, Safety and Tolerability of three doses of orally administered BMS-986368, a FAAH/MAGL Inhibitor, for the treatment of Spasticity in Participants with Multiple Sclerosis (BALANCE-MSS-1)

HREC: 2025.057
Principal Investigator: Dr Mark Marriott
Coordinator contact: Katherine Fazzolari
Funding: Commercial
Multiple sclerosis
Multiple Sclerosis
STAR MOG

A phase III randomised, double-blind, placebo-controlled, multicentre study to evaluate the efficacy and safety of treatment with corticoSTeroids at onset, And Rituximab during a relapse, of Myelin Oligodendrocyte Glycoprotein antibody-associated disease

HREC: 2025.022
Principal Investigator: Prof Tomas Kalincik
Coordinator contact: Katherine Fazzolari
Funding: Non-Commercial
Multiple sclerosis
Multiple Sclerosis
FiRMS EBV

Fatigue in Relapsing Multiple Sclerosis Epstein Barr Virus Treatment Trial – FiRMS EBV

HREC: 2024.137
Principal Investigator: Dr Izanne Roos
Coordinator contact: Katherine Fazzolari
Funding: Non-Commercial
Multiple sclerosis
Multiple Sclerosis
RESHAPE

CLOU064C12306: A randomized, open-label, parallel-group, non-inferiority study comparing efficacy, safety, and tolerability of remibrutinib after switching from ocrelizumab in participants living with relapsing multiple sclerosis, followed by open-label treatment with remibrutinib

HREC: 2025.026
Principal Investigator: Dr Ai-Lan Nguyen
Coordinator contact: Katherine Fazzolari
Funding: Commercial