effect overlay
activetrials
Stroke
Stroke
LOTUS

LOw dose combinations To improve stroke oUtcomeS (LOTUS)

HREC: 2025.053
Principal Investigator: Prof Bruce Campbell
Coordinator contact: Christine Shin
Funding: Non-Commercial
Multiple sclerosis
Multiple Sclerosis
RESHAPE

CLOU064C12306: A randomized, open-label, parallel-group, non-inferiority study comparing efficacy, safety, and tolerability of remibrutinib after switching from ocrelizumab in participants living with relapsing multiple sclerosis, followed by open-label treatment with remibrutinib

HREC: 2025.026
Principal Investigator: Dr Ai-Lan Nguyen
Coordinator contact: Katherine Fazzolari
Funding: Commercial
Stroke
Stroke
ACT GLOBAL

A multi-faCtorial, mulTi-arm, multi-staGe, randomised, gLOBal pLatform trial for Stroke (ACT-GLOBAL)

HREC: 2025.024
Principal Investigator: Prof Bruce Campbell
Coordinator contact: David Jackson
Funding: Non-Commercial
Movement Disorders
Movement Disorders
GAIN GNX

An Open-label Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GT-02287 in Participants with Parkinson’s Disease With or Without a Pathogenic GBA1 Mutation

HREC: 2025.016
Principal Investigator: Dr Andrew Evans
Coordinator contact: Reena Chopra
Funding: Commercial
Epilepsy
Epilepsy
Xenon 302

A Randomized, Double-blind, Placebo-Controlled, Multicenter Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of XEN1101 as Adjunctive Therapy in Focal-Onset Seizures (XTOLE3)

HREC: 2025.006
Principal Investigator: Dr John-Paul Nicolo
Coordinator contact: Karen Chidgey
Funding: Commercial